human MAX Adenovirus

Name 
Ad-h-MAX
Cat No 
ADV-215078
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ENC1.

ADV-215078
Ad-h-MAX

Ready-to-use Adenovirus expressing Human MAX (MYC associated factor X). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bHLHd4; class D basic helix-loop-helix protein 4; Myc-associated factor X; protein max
Description (eCommerce)
MAX (Myc-associated factor X) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation [taken from NCBI Entrez Gene (Gene ID: 4149)].
Description (Vector)
MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
Gene ID
4149
Gene Name (eCommerce)
MYC associated factor X
Gene Name (Vector)
MYC associated factor X
Gene Symbol
MAX
HGNC ID
HGNC:6913
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
291
Protein Name (eCommerce)
Protein max
RefSeq ID
NM_002382
RefSeq Synonyms
NM_197957, NM_145116, NM_145114, NM_145113, NM_145112, NM_002382, NM_001320415, NM_001271069, NM_001271068, BC036092, BC027924, BC025685, BC013669, BC004516, BC003525,
Research Areas
Apoptosis,B-cell Receptor Signaling,Breast Cancer,Cancer,Gene Expression,Immunology,Lung Cancer,MAPK Signaling,Neurobiology,Neurodevelopment,Signal Transduction,Transcription Factor/Regulator,Transcriptional Misregulation in Cancer
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
MAX (Myc-associated factor X) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation [taken from NCBI Entrez Gene (Gene ID: 4149)].
UniGene ID
Hs.712926
UniProt ID (eCommerce)
P61244

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.