human LRPPRC Adenovirus

Name 
Ad-h-LRPPRC
Cat No 
ADV-214513
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human EDN1.

ADV-214513
Ad-h-LRPPRC

Ready-to-use Adenovirus expressing Human LRPPRC (leucine rich pentatricopeptide repeat containing). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
130 kDa leucine-rich protein; CLONE-23970; GP130; leucine-rich PPR motif-containing protein, mitochondrial; leucine-rich PPR-motif containing; LRP 130; LRP130; LSFC; mitochondrial leucine-rich PPR motif-containing protein
Description (eCommerce)
LRPPRC is a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome [taken from NCBI Entrez Gene (Gene ID: 10128)].
Description (Vector)
LRPPRC encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.
Gene ID
10128
Gene Name (eCommerce)
leucine rich pentatricopeptide repeat containing
Gene Name (Vector)
leucine rich pentatricopeptide repeat containing
Gene Symbol
LRPPRC
HGNC ID
HGNC:15714
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4185
ORF Size (bp)
4185 bp
Protein Name (eCommerce)
Leucine-rich PPR motif-containing protein, mitochondrial
RefSeq ID
NM_133259
RefSeq Synonyms
NM_133259, BC130285, BC050311,
Research Areas
Cancer,Cytoskeleton,Interleukin Signaling,Mitochondrion,mRNA transport,RNA Binding,RNA Transport,Signal Transduction,TNF Signaling,Transcription Factor/Regulator,Transport
Research Areas (Faceted)
cancer,cell_biology,genetics,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
LRPPRC is a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome [taken from NCBI Entrez Gene (Gene ID: 10128)].
UniGene ID
Hs.368084
UniProt ID (eCommerce)
P42704

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.