human LPP Adenovirus

Name 
Ad-h-LPP
Cat No 
ADV-214463
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human LPP.

ADV-214463
Ad-h-LPP

Ready-to-use Adenovirus expressing Human LPP (LIM domain containing preferred translocation partner in lipoma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LIM domain-containing preferred translocation partner in lipoma; LIM protein; lipoma preferred partner; lipoma-preferred partner
Description (eCommerce)
Lipoma-preferred partner (LPP) may play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. LPP is also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q93052].
Description (Vector)
LPP encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. LPP is located at the junction of certain disease related chromosomal translocations which result in the expression of chimeric proteins that may promote tumor growth. Alternate splicing results in multiple transcript variants.
Gene ID
4026
Gene Name (eCommerce)
LIM domain containing preferred translocation partner in lipoma
Gene Name (Vector)
LIM domain containing preferred translocation partner in lipoma
Gene Symbol
LPP
HGNC ID
HGNC:6679
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1839
ORF Size (bp)
1839 bp
Protein Name (eCommerce)
Lipoma-preferred partner
RefSeq ID
NM_005578
RefSeq Synonyms
NM_005578, NM_001167672, NM_001167671, BC144076, BC130584,
Research Areas
EGFR Signaling,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Lipoma-preferred partner (LPP) may play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. LPP is also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q93052].
UniGene ID
Hs.444362
UniProt ID (eCommerce)
Q93052

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.