human LPIN2 Adenovirus

Name 
Ad-h-LPIN2
Cat No 
ADV-214457
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human LPIN2.

ADV-214457
Ad-h-LPIN2

Ready-to-use Adenovirus expressing Human LPIN2 (lipin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Lipin-2; phosphatidate phosphatase LPIN2
Description (eCommerce)
Lipin 2 plays important roles in controlling the metabolism of fatty acids at differents levels. It acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the endoplasmic reticulum membrane. Lipin 2 also acts as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q92539].
Description (Vector)
Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance.
Gene ID
9663
Gene Name (eCommerce)
lipin 2
Gene Name (Vector)
lipin 2
Gene Symbol
LPIN2
HGNC ID
HGNC:14450
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2691
ORF Size (bp)
2691 bp
Protein Name (eCommerce)
Phosphatidate phosphatase LPIN2
RefSeq ID
NM_014646
RefSeq Synonyms
NM_014646, BC160018, BC152448,
Research Areas
Metabolism/Metabolic Process,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Lipin 2 plays important roles in controlling the metabolism of fatty acids at differents levels. It acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the endoplasmic reticulum membrane. Lipin 2 also acts as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q92539].
UniGene ID
Hs.132342
UniProt ID (eCommerce)
Q92539

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.