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human LNPEP Adenovirus

Name 
Ad-h-LNPEP
Cat No 
ADV-214058
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human LNPEP.

ADV-214058
Ad-h-LNPEP

Ready-to-use Adenovirus expressing Human LNPEP (leucyl and cystinyl aminopeptidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
angiotensin IV receptor; AT (4) receptor; CAP; cystinyl aminopeptidase; insulin-regulated aminopeptidase; insulin-regulated membrane aminopeptidase; insulin-responsive aminopeptidase; IRAP; leucyl-cystinyl aminopeptidase; otase; oxytocinase; placental leucine aminopeptidase; PLAP; P-LAP; vasopressinase
Description (eCommerce)
Oxytocinase is a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 4012)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UIQ6].
Description (Vector)
LNPEP encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
4012
Gene Name (eCommerce)
leucyl and cystinyl aminopeptidase
Gene Name (Vector)
leucyl and cystinyl aminopeptidase
Gene Symbol
LNPEP
HGNC ID
HGNC:6656
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3078
ORF Size (bp)
3078 bp
Protein Name (eCommerce)
Leucyl-cystinyl aminopeptidase
RefSeq ID
NM_005575
RefSeq Synonyms
NM_175920, NM_005575, BC160010,
Research Areas
Antigen Processing and Presentation,Immunology,Metabolism/Metabolic Process,T-cell Receptor Signaling
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction
Species
human
Target Sentence
Oxytocinase is a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 4012)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UIQ6].
UniGene ID
Hs.656905
UniProt ID (eCommerce)
Q9UIQ6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.