human TNNC1 Adenovirus
This is an Adenovirus expressing Human TNNC1.
ADV-226127
Ad-h-TNNC1
Ready-to-use Adenovirus expressing Human TNNC1 (troponin C1, slow skeletal and cardiac type). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMD1Z; CMH13; TN-C; TNC; TNNC
Description (Vector)
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
Gene ID
7134
Gene Name (Vector)
troponin C1, slow skeletal and cardiac type
Gene Symbol
TNNC1
HGNC ID
HGNC:11943
ORF Size (aa)
486
RefSeq ID
NM_003280
RefSeq Synonyms
NM_003280, BC030244,
Species
human
UniGene ID
Hs.118845
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.