human ABCB6 Over-expression AAV

Name
AAV-h-ABCB6

Cat No
AAV-200061

Availability
4-5 weeks

This is an AAV expressing Human ABCB6.

AAV-200061

AAV-h-ABCB6

Ready-to-use AAV expressing Human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABC; ABC14; DUH3; LAN; MCOPCB7; MTABC3; PRP; PSHK2; umat

Description (Vector)

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Gene ID

10058

Gene Name (Vector)

ATP binding cassette subfamily B member 6 (Langereis blood group)

Gene Symbol

ABCB6

HGNC ID

HGNC:47

ORF Size (aa)

2529

ORF Size (bp)

2529 bp

RefSeq ID

NM_005689

RefSeq Synonyms

NM_005689, BC000559,

Species

human

UniGene ID

Hs.107911

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.