human AARS2 Over-expression AAV

Name
AAV-h-AARS2

Cat No
AAV-200029

Availability
4-5 weeks

This is an AAV expressing Human AARS2.

AAV-200029

AAV-h-AARS2

Ready-to-use AAV expressing Human AARS2 (alanyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AARSL; COXPD8; LKENP; MT-ALARS; MTALARS

Description (Vector)

AARS2 belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.

Gene ID

57505

Gene Name (Vector)

alanyl-tRNA synthetase 2, mitochondrial

Gene Symbol

AARS2

HGNC ID

HGNC:21022

ORF Size (aa)

2958

ORF Size (bp)

2958 bp

RefSeq ID

NM_020745

RefSeq Synonyms

NM_020745, BC131728,

Species

human

UniGene ID

Hs.158381

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.