human KIF13A Adenovirus
This is an Adenovirus expressing Human KIF13A.
ADV-213067
Ad-h-KIF13A
Ready-to-use Adenovirus expressing Human KIF13A (kinesin family member 13A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bA500C11.2; homolog of mouse KIF13A mannose-6-phosphate receptor transporter; kinesin-like protein KIF13A; kinesin-like protein RBKIN; RBKIN
Description (eCommerce)
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF13A is reported to transport the mannose-6-phosphate receptor from the trans-golgi network to the plasma membrane by associating with beta 1-adaptin in the AP-1 adaptor complex.
Description (Vector)
KIF13A encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants.
Gene ID
63971
Gene Name (eCommerce)
kinesin family member 13A
Gene Name (Vector)
kinesin family member 13A
Gene Symbol
KIF13A
HGNC ID
HGNC:14566
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5313
ORF Size (bp)
5313 bp
Protein Name (eCommerce)
Kinesin-like protein KIF13A
RefSeq ID
NM_022113
RefSeq Synonyms
NM_022113, NM_001243423, NM_001105568, NM_001105567, NM_001105566, BC127116, BC127115,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Golgi Apparatus,Lysosomal Transport,Protein Folding,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF13A is reported to transport the mannose-6-phosphate receptor from the trans-golgi network to the plasma membrane by associating with beta 1-adaptin in the AP-1 adaptor complex.
UniGene ID
Hs.189915
UniProt ID (eCommerce)
Q9H1H9
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.