human KDR Adenovirus

Name
Ad-h-KDR

Cat No
ADV-212862

Availability
4-5 weeks

This is an Adenovirus expressing Human KDR.

ADV-212862

Ad-h-KDR

Ready-to-use Adenovirus expressing Human KDR (kinase insert domain receptor). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CD309; FLK1; VEGFR; VEGFR2

Description (Vector)

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Gene ID

3791

Gene Name (Vector)

kinase insert domain receptor

Gene Symbol

KDR

HGNC ID

HGNC:6307

ORF Size (aa)

4071

ORF Size (bp)

4071 bp

RefSeq ID

NM_002253

RefSeq Synonyms

NM_002253, BC131822,

Species

human

UniGene ID

Hs.479756

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.