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human IPO4 Adenovirus

Name 
Ad-h-IPO4
Cat No 
ADV-212345
Availability
4-5 weeks

This is an Adenovirus expressing Human IPO4.

ADV-212345
Ad-h-IPO4

Ready-to-use Adenovirus expressing Human IPO4 (importin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Imp4; imp4b; importin-4; importin-4b; ran-binding protein 4; ranBP4
Description (eCommerce)
Importin 4 mediates the nuclear import of RPS3A. In vitro, it mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Additionally, along with importin 7, importin 4 has been shown to be involved in nuclear import of HIF-1alpha [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q8TEX9].
Gene ID
79711
Gene Name (eCommerce)
importin 4
Gene Name (Vector)
importin 4
Gene Symbol
IPO4
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3246
ORF Size (bp)
3246 bp
Protein Name (eCommerce)
Importin-4
RefSeq ID
NM_024658
RefSeq Synonyms
NM_024658, BC136759, BC110804,
Research Areas
Immunology,Signal Transduction,Transport
Research Areas (Faceted)
signal_transduction,immunology,cell_biology
Species
human
Target Sentence
Importin 4 mediates the nuclear import of RPS3A. In vitro, it mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Additionally, along with importin 7, importin 4 has been shown to be involved in nuclear import of HIF-1alpha [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q8TEX9].
UniGene ID
Hs.411865
UniProt ID (eCommerce)
Q8TEX9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.