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human GJB2 Adenovirus

Name 
Ad-h-GJB2
Cat No 
ADV-209923
Availability
4-5 weeks

This is an Adenovirus expressing Human GJB2.

ADV-209923
Ad-h-GJB2

Ready-to-use Adenovirus expressing Human GJB2 (gap junction protein beta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CX26; DFNA3; DFNA3A; DFNB1; DFNB1A; HID; KID; NSRD1; PPK
Description (Vector)
GJB2 encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.
Gene ID
2706
Gene Name (Vector)
gap junction protein beta 2
Gene Symbol
GJB2
HGNC ID
HGNC:4284
ORF Size (aa)
681
ORF Size (bp)
681 bp
RefSeq ID
NM_004004
RefSeq Synonyms
NM_004004, BC071703, BC017048,
Species
human
UniGene ID
Hs.714494

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.