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human CIRH1A shRNA silencing AAV

Name 
AAV-h-CIRH1A-shRNA
Cat No 
shAAV-205289
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UTP4.

shAAV-205289
AAV-h-CIRH1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UTP4 (UTP4, small subunit processome component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CIRH1A; CIRHIN; NAIC; TEX292
Description (Vector)
CIRH1A encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence.
Gene ID
84916
Gene Name (Vector)
UTP4, small subunit processome component
Gene Symbol
UTP4
HGNC ID
HGNC:1983
ORF Size (aa)
2061
ORF Size (bp)
2061 bp
RefSeq ID
NM_032830
RefSeq Synonyms
NM_032830, NM_001318391, BC009348,
Species
human
UniGene ID
Hs.461113

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.