Vascular endothelial growth factor B (isoform Vegf-b186) Adenovirus

Name 
Ad-VEGF-B
Cat No 
1550
Availability
Immediate
Categories
Adenovirus, Over-Expression

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include FGF, PDGF, vascular endothelial growth factor (VEGF), VEGF-B, VEGF-C, VEGF-D (or FIGF), EG-VEGF and placenta growth factor (PlGF). This adenovirus contains a human VEGF-B186.

1550
Ad-VEGF-B

Ready-to-use Vascular endothelial growth factor B (isoform Vegf-b186) Adenovirus. Ad-VEGF-B, Vascular endothelial growth factor B, VRF, VEGFB, VEGFL adenovirus 1550 VEGF-B186

$475.00
Request Volume Pricing or Customization

Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
VEGFL; VRF
Description (Vector)
VEGFB encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Gene ID
7423
Gene Name (Vector)
vascular endothelial growth factor B
Gene Symbol
VEGFB
HGNC ID
HGNC:12681
ORF Size (aa)
624
RefSeq ID
NM_003377
RefSeq Synonyms
NM_003377, NM_001243733, BC008818,
Species
human
UniGene ID
Hs.78781

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.