Arrestin, beta 1 Adenovirus

Name 
Ad-Arrestin-1(beta)
Cat No 
1529
Availability
Immediate
Categories
Adenovirus, Over-Expression

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.

1529
Ad-Arrestin-1(beta)

Ready-to-use Arrestin, beta 1 Adenovirus. Ad-Arrestin-1(beta), “Arrestin, beta 1”, ARB1, ARR1, ARRB1, b-Arrestin-1 adenovirus 1529

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
ARB1; ARR1; arrestin 2; Arrestin beta-1; beta-arrestin-1; non-visual arrestin-2
Description (eCommerce)
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions [taken from NCBI Entrez Gene (Gene ID: 408)].
Gene ID
408
Gene Name (eCommerce)
arrestin beta 1
Gene Name (Vector)
arrestin beta 1
Gene Symbol
ARRB1
HGNC ID
HGNC:711
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
Protein Name (eCommerce)
Beta-arrestin-1
RefSeq ID
NM_004041
RefSeq Synonyms
NM_020251, NM_004041, BC003636,
Research Areas
Cancer,Cardiology,Cardiovascular,Golgi Apparatus,Histone Modification,Interleukin Signaling,Kinase/Phosphatase,MAPK Signaling,Neurobiology,Notch Signaling,Rho Signaling,Signal Transduction,Transcription Factor/Regulator,Ubiquitination,Wnt Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions [taken from NCBI Entrez Gene (Gene ID: 408)].
UniGene ID
Hs.625320
UniProt ID (eCommerce)
P49407

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.