DNA-damage-inducible transcript 3 Adenovirus

Name 
Ad-C/EBP-Zeta
Cat No 
1527
Availability
Immediate
Categories
Adenovirus, Over-Expression

C/EBP (CCAAT-enhancer binding protein) is a heat-stable, sequence-specific DNA-binding transcription factor that was initially purified from rat liver nuclei. C/EBP binds DNA through a bipartite structural motif and appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP-beta, C/EBP-gamma, C/EBP-zeta and C/EBP-epsilon, all of which exhibit similar DNA-binding specificities and affinities with C/EBP-alpha. Furthermore, C/EBP-beta and C/EBP-zeta readily form heterodimers with each other as well as with C/EBP-alpha.

1527
Ad-C/EBP-Zeta

Ready-to-use DNA-damage-inducible transcript 3 Adenovirus. Ad-C/EBP-Zeta, DNA-damage-inducible transcript 3, CHOP, CEBPZ, DDIT3, CHOP10, GADD153, C/EBP(zeta) adenovirus 1527

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume
200 µL

Gene Reference Data

Alternate Names
CEBPZ; CHOP; CHOP-10; CHOP10; GADD153
Description (Vector)
DDIT3 encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Gene ID
1649
Gene Name (Vector)
DNA damage inducible transcript 3
Gene Symbol
DDIT3
HGNC ID
HGNC:2726
ORF Size (aa)
510
ORF Size (bp)
510 bp
RefSeq ID
NM_004083
RefSeq Synonyms
NM_004083, NM_001195057, NM_001195056, NM_001195055, NM_001195054, NM_001195053, BC003637,
Species
human
UniGene ID
Hs.690217

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.