Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) Adenovirus

Name 
Ad-p19/INK4D
Cat No 
1526
Availability
Immediate
Categories
Adenovirus, Over-Expression

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis.

1526
Ad-p19/INK4D

Ready-to-use Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) Adenovirus. Ad-p19/INK4D, “Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)”, P19, INK4D, CDKN2D, P19-INK4D, p19/INK4D adenovirus 1526

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume
200 µL

Gene Reference Data

Alternate Names
INK4D; p19; p19-INK4D
Description (Vector)
CDKN2D is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
Gene ID
1032
Gene Name (Vector)
cyclin dependent kinase inhibitor 2D
Gene Symbol
CDKN2D
HGNC ID
HGNC:1790
ORF Size (aa)
501
ORF Size (bp)
501 bp
RefSeq ID
NM_079421
RefSeq Synonyms
NM_079421, NM_001800, BC001822,
Species
human
UniGene ID
Hs.435051

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.