Neutrophil cytosolic factor 1 Adenovirus
The superoxide-generating NADPH oxidase is present in phagocytes, neuroepithelial bodies, vascular smooth muscle cells and endothelial cells. It includes a membrane-bound flavocytochrome containing gp91-phox, Nox4 and p22-phox, and the cytosolic proteins, p40-phox, p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome cytochrome b558 to form the active enzyme complex. Mox1 is largely similar to gp91 and is involved in regulating NADPH oxidase activity in non-phagocytic cells.
1494
Ad-p47Phox
Ready-to-use Neutrophil cytosolic factor 1 Adenovirus. Ad-p47Phox, Neutrophil cytosolic factor 1, NCF1,NOXO2,P47PHOX adenovirus 1494
Gene Reference Data
Alternate Names
NCF1A; NOXO2; p47phox; SH3PXD1A
Description (Vector)
NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.
Gene ID
653361
Gene Name (Vector)
neutrophil cytosolic factor 1
Gene Symbol
NCF1
HGNC ID
HGNC:7660
ORF Size (aa)
1173
ORF Size (bp)
1173 bp
RefSeq ID
NM_000265
RefSeq Synonyms
NM_000265, BC065731, BC002816,
Species
human
UniGene ID
Hs.647047
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.