human DMBT1 Adenovirus
This is an Adenovirus expressing Human DMBT1.
ADV-207079
Ad-h-DMBT1
Ready-to-use Adenovirus expressing Human DMBT1 (deleted in malignant brain tumors 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GP340; muclin; SAG; SALSA
Description (Vector)
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Gene ID
1755
Gene Name (Vector)
deleted in malignant brain tumors 1
Gene Symbol
DMBT1
HGNC ID
HGNC:2926
ORF Size (aa)
4989
ORF Size (bp)
4989 bp
RefSeq ID
NM_004406
RefSeq Synonyms
NM_017579, NM_007329, NM_004406, NM_001320644, BC153299,
Species
human
UniGene ID
Hs.279611
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.