human DLGAP5 Adenovirus

Name 
Ad-h-DLGAP5
Cat No 
ADV-207052
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human C8orf44.

ADV-207052
Ad-h-DLGAP5

Ready-to-use Adenovirus expressing Human DLGAP5 (DLG associated protein 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DAP-5; Discs large homolog 7; discs large homolog associated protein 5; discs, large homolog 7; disks large-associated protein 5; disks large-associated protein DLG7; DLG7; hepatoma up-regulated protein; HURP
Description (eCommerce)
HURP/DLG7 (Hepatoma Up-Regulated Protein/Disks Large Homolog 7) is a member of the MAGUK (membrane-associated guanylate kinase) family of scaffolding proteins. There are seven DLG homologs in mammals that play important roles in regulating proliferation, epithelial cell polarity, cell adhesion, and synapse formation. HURP/DLG7 has been identified as a microtubule-associated protein (MAP) that colocalizes with the mitotic spindle and functions as a mitotic regulator. HURP/DLG7 is required for microtubule attachment and efficient capture of kinetochores, as well as timely chromosome congression. HURP/DLG7 is up-regulated in human cancer cells and may contribute to tumorigenesis.
Gene ID
9787
Gene Name (eCommerce)
DLG associated protein 5
Gene Name (Vector)
DLG associated protein 5
Gene Symbol
DLGAP5
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2541
ORF Size (bp)
2541 bp
Protein Name (eCommerce)
Disks large-associated protein 5
RefSeq ID
NM_014750
RefSeq Synonyms
NM_014750, NM_001146015, BC016276, BC010658,
Research Areas
Cancer,Cell Cycle,Cell Division,Cytoskeleton,Kinase/Phosphatase,Signal Transduction,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
HURP/DLG7 (Hepatoma Up-Regulated Protein/Disks Large Homolog 7) is a member of the MAGUK (membrane-associated guanylate kinase) family of scaffolding proteins. There are seven DLG homologs in mammals that play important roles in regulating proliferation, epithelial cell polarity, cell adhesion, and synapse formation. HURP/DLG7 has been identified as a microtubule-associated protein (MAP) that colocalizes with the mitotic spindle and functions as a mitotic regulator. HURP/DLG7 is required for microtubule attachment and efficient capture of kinetochores, as well as timely chromosome congression. HURP/DLG7 is up-regulated in human cancer cells and may contribute to tumorigenesis.
UniGene ID
Hs.77695
UniProt ID (eCommerce)
Q15398

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.