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human DLG1 Adenovirus

Name 
Ad-h-DLG1
Cat No 
ADV-207040
Availability
4-5 weeks

This is an Adenovirus expressing Human DLG1.

ADV-207040
Ad-h-DLG1

Ready-to-use Adenovirus expressing Human DLG1 (discs large MAGUK scaffold protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
discs large homolog 1, scribble cell polarity complex component; disks large homolog 1; dJ1061C18.1.1; DLGH1; hdlg; presynaptic protein SAP97; SAP97; SAP-97; synapse-associated protein 97
Description (eCommerce)
SAP97 (synapse-associated protein 97) is a scaffolding protein that contains three PDZ domains, one SH3 domain, one L27 domain, and one guanylate kinase-like domain. SAP97 has been found to control ion channel clustering at post-synaptic densities in neural cells and to also play a role in adherens junction assembly, and the recruitment of signaling molecules to discreet plasma membrane domains.
Description (Vector)
DLG1 encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known.
Gene ID
1739
Gene Name (eCommerce)
discs large MAGUK scaffold protein 1
Gene Name (Vector)
discs large MAGUK scaffold protein 1
Gene Symbol
DLG1
HGNC ID
HGNC:2900
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2679
ORF Size (bp)
2679 bp
Protein Name (eCommerce)
Disks large homolog 1
RefSeq ID
NM_004087
RefSeq Synonyms
NM_004087, NM_001290983, NM_001204388, NM_001204387, NM_001204386, NM_001098424, BC144651, BC140841,
Research Areas
Axon Guidance,BDNF Signaling,Cancer,Cell Cycle,Cytoskeleton,Golgi Apparatus,Hippo Signaling,Host-Virus Interactions,Immunology,Neurobiology,Neurodevelopment,Signal Transduction,Synapse,T-cell Receptor Signaling,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,neurobiology,signal_transduction
Species
human
Target Sentence
SAP97 (synapse-associated protein 97) is a scaffolding protein that contains three PDZ domains, one SH3 domain, one L27 domain, and one guanylate kinase-like domain. SAP97 has been found to control ion channel clustering at post-synaptic densities in neural cells and to also play a role in adherens junction assembly, and the recruitment of signaling molecules to discreet plasma membrane domains.
UniGene ID
Hs.292549
UniProt ID (eCommerce)
Q12959

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.