Aryl hydrocarbon receptor nuclear translocator-like Adenovirus

Name 
Ad-bMAL1
Cat No 
1445
Availability
Immediate
Categories
Adenovirus, Over-Expression

The Per-Arnt-Sim (PAS) domain was identified as a 270 amino acid motif that mediates associations among various PAS family transcription factors. PAS domain family members include period proteins (Per1, Per2 and Per3), Arnt 1 (also designated HIF-1beta), Arnt 2, Ah Receptor, BMAL1 (for Brain and Muscle Arnt-like protein 1; also designated Arnt 3, TIC, JAP3 or MOP3), Clock, single-minded proteins (SIM1 and SIM2) and hypoxia-inducible factors such as HIF-1(alpha) (also designated MOP1), EPAS-1 (also designated HIF-2(alpha), MOP2 or HLF) and HIF-3(alpha). The PAS family also contains a neuronal specific transcription factor known as NPAS2 that is involved the development and maintenance of learning and memory pathways. NPAS2, which is also designated PAS 4/MOP4, associates with MOP3 to activate transcription. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes.

1445
Ad-bMAL1

Ready-to-use Aryl hydrocarbon receptor nuclear translocator-like Adenovirus. Ad-bMAL1, Aryl hydrocarbon receptor nuclear translocator-like, TIC,JAP3,MOP3,ARNTL,BMAL1,PASD3,BMAL1C,MGC47515 adenovirus 1445

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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
ARNT-like protein 1, brain and muscle; aryl hydrocarbon receptor nuclear translocator-like protein 1; basic helix-loop-helix family member e5; basic-helix-loop-helix-PAS orphan MOP3; basic-helix-loop-helix-PAS protein MOP3; bHLHe5; bHLH-PAS protein JAP3; BMAL1; BMAL1c; brain and muscle ARNT-like 1; class E basic helix-loop-helix protein 5; JAP3; member of PAS protein 3; member of PAS superfamily 3; MOP3; PAS domain containing 3; PAS domain-containing protein 3; PASD3; testis tissue sperm-binding protein Li 50e; TIC
Description (eCommerce)
BMAL1 [brain and muscle aryl hydrocarbon receptor nuclear translocator (ARNT)-like 1] is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes [taken from NCBI Entrez Gene (GeneID: 406)].
Description (Vector)
ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
406
Gene Name (eCommerce)
aryl hydrocarbon receptor nuclear translocator like
Gene Name (Vector)
aryl hydrocarbon receptor nuclear translocator like
Gene Symbol
ARNTL
HGNC ID
HGNC:701
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1878
ORF Size (bp)
1878 bp
Protein Name (eCommerce)
Aryl hydrocarbon receptor nuclear translocator-like protein 1
RefSeq ID
NM_001178
RefSeq Synonyms
NM_001297724, NM_001297722, NM_001297719, NM_001178, NM_001030273, NM_001030272, BC041129, BC031214, BC016674,
Research Areas
Aging,Hedgehog Signaling,Host-Virus Interactions,Metabolism/Metabolic Process,Neurobiology,RNA Binding,Signal Transduction,Transcription Factor/Regulator,Transport
Research Areas (Faceted)
cell_biology,infectious_disease,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
BMAL1 [brain and muscle aryl hydrocarbon receptor nuclear translocator (ARNT)-like 1] is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes [taken from NCBI Entrez Gene (GeneID: 406)].
UniGene ID
Hs.65734
UniProt ID (eCommerce)
O00327

Related Citations

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.