human DFNB31 Adenovirus

Name 
Ad-h-DFNB31
Cat No 
ADV-206901
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human DFNB31.

ADV-206901
Ad-h-DFNB31

Ready-to-use Adenovirus expressing Human WHRN (whirlin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CIP98; DFNB31; PDZD7B; USH2D; WI
Description (Vector)
DFNB31 is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene ID
25861
Gene Name (Vector)
whirlin
Gene Symbol
WHRN
HGNC ID
HGNC:16361
ORF Size (aa)
2721
ORF Size (bp)
2721 bp
RefSeq ID
NM_015404
RefSeq Synonyms
NM_015404, NM_001346890, NM_001173425, NM_001083885, BC142684, BC142614, BC136416,
Species
human
UniGene ID
Hs.93836

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.