Suppressor of cytokine signaling 3 Adenovirus

Name 
Ad-SOCS3
Cat No 
1440
Availability
Immediate
Categories
Adenovirus, Over-Expression

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

1440
Ad-SOCS3

Ready-to-use Suppressor of cytokine signaling 3 Adenovirus. Ad-SOCS3, Suppressor of cytokine signaling 3, CIS3,CISH3,SOCS3,SSI-3,SOCS-3,MGC71791 adenovirus 1440

$475.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Description (Vector)
SOCS3 encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Gene ID
9021
Gene Name (Vector)
suppressor of cytokine signaling 3
Gene Symbol
SOCS3
HGNC ID
HGNC:19391
ORF Size (aa)
678
RefSeq ID
NM_003955
RefSeq Synonyms
NM_003955, BC060858,
Species
human
UniGene ID
Hs.527973

Related Citations

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.