Angiotensin II receptor-like 1 Adenovirus
There are at least two distinct receptor subtypes of angiotensin II: angiotensin II receptor, type 1 (AGTR1) and angiotensin II receptor, type 2 (AGTR2). Most of the effects of angiotensin II are mediated by the AGTR1 receptor. This gene is related to the AGTR1 gene by sequence similarity. It was cloned based on a conserved transmembrane domain found in members of the G protein-coupled receptor (GPCR) gene family
1428
Ad-AGTR-L1
Ready-to-use Angiotensin II receptor-like 1 Adenovirus. Ad-AGTR-L1, Angiotensin II receptor-like 1, APJ, AGTRL1, AGTR-L1 adenovirus 1428
Gene Reference Data
Alternate Names
AGTRL1; APJ; APJR; HG11
Description (Vector)
APLNR encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
Gene ID
187
Gene Name (Vector)
apelin receptor
Gene Symbol
APLNR
HGNC ID
HGNC:339
ORF Size (aa)
1143
ORF Size (bp)
1143 bp
RefSeq ID
NM_005161
RefSeq Synonyms
NM_005161, BC032688,
Species
human
UniGene ID
Hs.438311
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.