human DBT Adenovirus

Name
Ad-h-DBT

Cat No
ADV-206629

Availability
4-5 weeks

This is an Adenovirus expressing Human DBT.

ADV-206629

Ad-h-DBT

Ready-to-use Adenovirus expressing Human DBT (dihydrolipoamide branched chain transacylase E2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BCATE2; BCKAD-E2; BCKADE2; BCOADC-E2; E2; E2B

Description (Vector)

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene ID

1629

Gene Name (Vector)

dihydrolipoamide branched chain transacylase E2

Gene Symbol

DBT

HGNC ID

HGNC:2698

ORF Size (aa)

1449

ORF Size (bp)

1449 bp

RefSeq ID

NM_001918

RefSeq Synonyms

NM_001918, BC016675,

Species

human

UniGene ID

Hs.709187

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.