vascular endothelial growth factor D Adenovirus

Name 
Ad-VEGF-D
Cat No 
1418
Availability
Immediate
Categories
Adenovirus, Over-Expression

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include FGF, PDGF, vascular endothelial growth factor (VEGF), VEGF-B, VEGF-C, VEGF-D (or FIGF), EG-VEGF and placenta growth factor (PlGF). VEGF-D undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.

1418
Ad-VEGF-D

Ready-to-use vascular endothelial growth factor D Adenovirus. Ad-VEGF-D, vascular endothelial growth factor D, FIGF,VEGFD,VEGF-D adenovirus 1418

$475.00

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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume
200 µL

Gene Reference Data

Alternate Names
FIGF; VEGF-D
Description (Vector)
FIGF is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus.
Gene ID
2277
Gene Name (Vector)
vascular endothelial growth factor D
Gene Symbol
VEGFD
HGNC ID
HGNC:3708
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
RefSeq ID
NM_004469
RefSeq Synonyms
NM_004469, BC027948,
Species
human
UniGene ID
Hs.11392

Related Citations

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.