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human CYTH1 Adenovirus

Name 
Ad-h-CYTH1
Cat No 
ADV-206544
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CYTH1.

ADV-206544
Ad-h-CYTH1

Ready-to-use Adenovirus expressing Human CYTH1 (cytohesin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B2-1; CYTOHESIN-1; D17S811E; PSCD1; SEC7
Description (Vector)
CYTH1 is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.
Gene ID
9267
Gene Name (Vector)
cytohesin 1
Gene Symbol
CYTH1
HGNC ID
HGNC:9501
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_004762
RefSeq Synonyms
NM_017456, NM_004762, NM_001292019, NM_001292018, BC050452, BC038385,
Species
human
UniGene ID
Hs.191215

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.