SMAD, mothers against DPP homolog 5 (Drosophila) Adenovirus

Name 
Ad-SMAD5
Cat No 
1370
Availability
Immediate
Categories
Adenovirus, Over-Expression

Mammalian homologs of the Drosophila Mad gene include Smad1 (also designated Madr1 or JV4-1), Smad2 (also designated Madr2 or JV18-1), Smad3, Smad4 (also designated DPC4), Smad5, Smad6, Smad7 and Smad8 (also designated Smad9). Smad1 and Smad5 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGFb and activin-mediated growth modulation. Smad4 is required for all of the above activities and necessitates FAST-1 for DNA binding. Smad6 and Smad7 regulate the response to activin/ TGF-beta signaling by interfering with TGF-beta-mediated phosphorylation of other Smad family members.

1370
Ad-SMAD5

Ready-to-use SMAD, mothers against DPP homolog 5 (Drosophila) Adenovirus. Ad-SMAD5, “SMAD, mothers against DPP homolog 5 (Drosophila)”, DWFC,JV5-1,MADH5,SMAD5 adenovirus 1370

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
DWFC; JV5-1; MADH5
Description (Vector)
SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
4090
Gene Name (Vector)
SMAD family member 5
Gene Symbol
SMAD5
HGNC ID
HGNC:6771
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_001001419
RefSeq Synonyms
NM_005903, NM_001001420, NM_001001419, BC009682,
Species
human
UniGene ID
Hs.167700

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.