CTGF Adenovirus

Name 
Ad-CTGF
Cat No 
1352
Availability
Immediate
Categories
Adenovirus, Over-Expression

The CCN (CTGF/Cyr61/NOV) family of genes presently consists of six distinct members, which encode proteins that participate in fundamental biological processes such as cell proliferation, adhesion, migration, differentiation, wound healing, angiogenesis, and several pathologies including fibrosis and tumorigenesis. Whereas Cyr61 and CTGF act as positive regulators of cell growth, nov (nephroblastoma overexpressed) provides the first example of a CCN protein with negative regulatory properties and the first example of aberrant expression being associated with tumor development. The subsequent discovery of the WISP proteins has broadened the variety of functions attributed to the CCN family of proteins and has impacted previous observations relating to these protein in other biological setting.

1352
Ad-CTGF

Ready-to-use CTGF Adenovirus. Ad-CTGF, CTGF, CTGF adenovirus 1352

$690.00
Request Volume Pricing or Customization

Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
CCN2; HCS24; IGFBP8; NOV2
Description (Vector)
CTGF is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.
Gene ID
1490
Gene Name (Vector)
connective tissue growth factor
Gene Symbol
CTGF
HGNC ID
HGNC:2500
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
RefSeq ID
NM_001901
RefSeq Synonyms
NM_001901, BC087839,
Species
human
UniGene ID
Hs.591346

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.