human AGFG1 Adenovirus

Name 
Ad-h-AGFG1
Cat No 
ADV-200556
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human AGFG1.

ADV-200556
Ad-h-AGFG1

Ready-to-use Adenovirus expressing Human AGFG1 (ArfGAP with FG repeats 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
arf-GAP domain and FG repeat-containing protein 1; arf-GAP domain and FG repeats-containing protein 1; HIV-1 Rev-binding protein; HRB; hRIP, Rev interacting protein; nucleoporin-like protein RIP; RAB; Rab, Rev/Rex activation domain-binding protein; rev/Rex activation domain-binding protein; rev-interacting protein; RIP
Description (eCommerce)
NUPL or hRIP (human Rev interacting protein) was originally identified in a yeast two-hybrid screen for proteins that interact with the Rev protein of the human immunodeficiency virus type 1 (HIV-1). Structurally, hRIP contains an ARFGAP (ARF GTPase-activating protein) domain. hRIP was found to have homology with nucleoporins; thus it is also referred to as nucleoporin-like protein (NUPL) RIP. hRIP is essential to HIV-1 replication but not for cell viability, and it appears to be important for the export of HIV-1 RNA from the perinuclear region to the cytoplasm.
Description (Vector)
AGFG1 is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
3267
Gene Name (eCommerce)
ArfGAP with FG repeats 1
Gene Name (Vector)
ArfGAP with FG repeats 1
Gene Symbol
AGFG1
HGNC ID
HGNC:5175
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1689
ORF Size (bp)
1689 bp
Protein Name (eCommerce)
Arf-GAP domain and FG repeat-containing protein 1
RefSeq ID
NM_004504
RefSeq Synonyms
NM_004504, NM_001135189, NM_001135188, NM_001135187, BC096275, BC096274, BC096273, BC096272, BC030592,
Research Areas
Golgi Apparatus,Host-Virus Interactions,mRNA transport,RNA Binding,RNA Transport,Spermatogenesis,Transport,Zinc-finger
Research Areas (Faceted)
cell_biology,developmental_biology,genetics,infectious_disease,transcription_translation
Species
human
Target Sentence
NUPL or hRIP (human Rev interacting protein) was originally identified in a yeast two-hybrid screen for proteins that interact with the Rev protein of the human immunodeficiency virus type 1 (HIV-1). Structurally, hRIP contains an ARFGAP (ARF GTPase-activating protein) domain. hRIP was found to have homology with nucleoporins; thus it is also referred to as nucleoporin-like protein (NUPL) RIP. hRIP is essential to HIV-1 replication but not for cell viability, and it appears to be important for the export of HIV-1 RNA from the perinuclear region to the cytoplasm.
UniGene ID
Hs.352962
UniProt ID (eCommerce)
P52594

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.