human ACSL4 Adenovirus

Name 
Ad-h-ACSL4
Cat No 
ADV-200251
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ACSL4.

ADV-200251
Ad-h-ACSL4

Ready-to-use Adenovirus expressing Human ACSL4 (acyl-CoA synthetase long-chain family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ACS4; acyl-CoA synthetase 4; FACL4; fatty-acid-Coenzyme A ligase, long-chain 4; LACS 4; LACS4; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; long-chain-fatty-acid--CoA ligase 4; MRX63; MRX68
Description (eCommerce)
ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome [taken from NCBI Entrez Gene (Gene ID: 2182)].
Description (Vector)
ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
Gene ID
2182
Gene Name (eCommerce)
acyl-CoA synthetase long chain family member 4
Gene Name (Vector)
acyl-CoA synthetase long-chain family member 4
Gene Symbol
ACSL4
HGNC ID
HGNC:3571
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2013
ORF Size (bp)
2013 bp
Protein Name (eCommerce)
Long-chain-fatty-acid--CoA ligase 4
RefSeq ID
NM_004458
RefSeq Synonyms
NM_022977, NM_004458, NM_001318510, NM_001318509, BC034959,
Research Areas
Interleukin Signaling,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology,metabolism,cell_biology,neurobiology
Species
human
Target Sentence
ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome [taken from NCBI Entrez Gene (Gene ID: 2182)].
UniGene ID
Hs.268785
UniProt ID (eCommerce)
O60488

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.