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rat RAD18 Over-expression AAV

Name 
AAV-r-RAD18
Cat No 
AAV-295111
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Rad18.

AAV-295111
AAV-r-RAD18

Ready-to-use AAV expressing Rat Rad18 (RAD18 E3 ubiquitin protein ligase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.
Gene ID
362412
Gene Name (Vector)
RAD18 E3 ubiquitin protein ligase
Gene Symbol
Rad18
ORF Size (aa)
1485
ORF Size (bp)
1485 bp
RefSeq ID
NM_001077673
RefSeq Synonyms
NM_001077673, BC127510,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.