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rat SREBF2 Over-expression AAV

Name 
AAV-r-SREBF2
Cat No 
AAV-294206
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Srebf2.

AAV-294206
AAV-r-SREBF2

Ready-to-use AAV expressing Rat Srebf2 (sterol regulatory element binding transcription factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Srebf2_retired; SREBP-2; SREBP2
Description (Vector)
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Gene ID
300095
Gene Name (Vector)
sterol regulatory element binding transcription factor 2
Gene Symbol
Srebf2
ORF Size (aa)
3402
ORF Size (bp)
3402 bp
RefSeq ID
NM_001033694
RefSeq Synonyms
NM_001033694, BC101902,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.