rat MBP Over-expression AAV
This is an AAV expressing Rat Mbp.
AAV-293885
AAV-r-MBP
Ready-to-use AAV expressing Rat Mbp (myelin basic protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Mbps
Description (Vector)
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Gene ID
24547
Gene Name (Vector)
myelin basic protein
Gene Symbol
Mbp
ORF Size (aa)
387
RefSeq ID
NM_001025289
RefSeq Synonyms
NM_017026, NM_001025294, NM_001025293, NM_001025292, NM_001025291, NM_001025289, BC094522, BC084713,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.