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rat CIR Over-expression AAV

Name 
AAV-r-CIR
Cat No 
AAV-292350
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Cir1.

AAV-292350
AAV-r-CIR

Ready-to-use AAV expressing Rat Cir1 (corepressor interacting with RBPJ, 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1700023b02rik; Cir; RGD1309199
Description (Vector)
CIR1 may modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
Gene ID
362149
Gene Name (Vector)
corepressor interacting with RBPJ, 1
Gene Symbol
Cir1
ORF Size (aa)
1356
ORF Size (bp)
1356 bp
RefSeq ID
NM_001007799
RefSeq Synonyms
NM_001007799, BC085869,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.