rat DNM1L Over-expression AAV

Name
AAV-r-DNM1L

Cat No
AAV-292343

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Rat Dnm1l.

AAV-292343

AAV-r-DNM1L

Ready-to-use AAV expressing Rat Dnm1l (dynamin 1-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DLP1; Dnml1; Drp1

Description (Vector)

Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport|Function: Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.

Gene ID

114114

Gene Name (Vector)

dynamin 1-like

Gene Symbol

Dnm1l

ORF Size (aa)

2151

ORF Size (bp)

2151 bp

RefSeq ID

NM_053655

RefSeq Synonyms

NM_053655, BC085843,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.