rat DNM1L shRNA silencing AAV

Name 
AAV-r-DNM1L-shRNA
Cat No 
shAAV-292343
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Dnm1l.

shAAV-292343
AAV-r-DNM1L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Dnm1l (dynamin 1-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
92
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DLP1; Dnml1; Drp1
Description (Vector)
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport|Function: Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
Gene ID
114114
Gene Name (Vector)
dynamin 1-like
Gene Symbol
Dnm1l
ORF Size (aa)
2151
ORF Size (bp)
2151 bp
RefSeq ID
NM_053655
RefSeq Synonyms
NM_053655, BC085843,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.