rat MCAM Over-expression AAV
This is an AAV expressing Rat Mcam.
AAV-292100
AAV-r-MCAM
Ready-to-use AAV expressing Rat Mcam (melanoma cell adhesion molecule). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD146; Muc18
Description (Vector)
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Gene ID
78967
Gene Name (Vector)
melanoma cell adhesion molecule
Gene Symbol
Mcam
ORF Size (aa)
1821
ORF Size (bp)
1821 bp
RefSeq ID
NM_023983
RefSeq Synonyms
NM_023983, NM_001034009, BC070916,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.