rat HMGCR Over-expression AAV

Name
AAV-r-HMGCR

Cat No
AAV-290330

Availability
4-5 weeks

This is an AAV expressing Rat Hmgcr.

AAV-290330

AAV-r-HMGCR

Ready-to-use AAV expressing Rat Hmgcr (3-hydroxy-3-methylglutaryl-CoA reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

3H3M

Description (Vector)

Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Gene ID

25675

Gene Name (Vector)

3-hydroxy-3-methylglutaryl-CoA reductase

Gene Symbol

Hmgcr

ORF Size (aa)

2664

ORF Size (bp)

2664 bp

RefSeq ID

NM_013134

RefSeq Synonyms

NM_013134, BC064654,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.