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mouse GDF9 Over-expression AAV

Name 
AAV-m-GDF9
Cat No 
AAV-281276
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Gdf9.

AAV-281276
AAV-m-GDF9

Ready-to-use AAV expressing Mouse Gdf9 (growth differentiation factor 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Gdf-9
Description (Vector)
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
Gene ID
14566
Gene Name (Vector)
growth differentiation factor 9
Gene Symbol
Gdf9
ORF Size (aa)
1326
ORF Size (bp)
1326 bp
RefSeq ID
NM_008110
RefSeq Synonyms
NM_008110, BC052667,
Species
mouse
UniGene ID
Mm.9714

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.