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mouse WEE2 Over-expression AAV

Name 
AAV-m-WEE2
Cat No 
AAV-281204
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Wee2.

AAV-281204
AAV-m-WEE2

Ready-to-use AAV expressing Mouse Wee2 (WEE1 homolog 2 (S. pombe)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Gm1065; Wee1B
Description (Vector)
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
Gene ID
381759
Gene Name (Vector)
WEE1 homolog 2 (S. pombe)
Gene Symbol
Wee2
ORF Size (aa)
1668
ORF Size (bp)
1668 bp
RefSeq ID
NM_201370
RefSeq Synonyms
NM_201370, BC080784, BC052883,
Species
mouse
UniGene ID
Mm.20593

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.