mouse DNMT3L Over-expression AAV
This is an AAV expressing Mouse Dnmt3l.
AAV-280690
AAV-m-DNMT3L
Ready-to-use AAV expressing Mouse Dnmt3l (DNA (cytosine-5-)-methyltransferase 3-like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D6Ertd14e; ecat7
Description (Vector)
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Gene ID
54427
Gene Name (Vector)
DNA (cytosine-5-)-methyltransferase 3-like
Gene Symbol
Dnmt3l
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
RefSeq ID
NM_019448
RefSeq Synonyms
NM_019448, NM_001284200, NM_001284199, NM_001284198, NM_001284197, NM_001081695, BC083147,
Species
mouse
UniGene ID
Mm.13433
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.