mouse CDH1 Over-expression AAV

Name
AAV-m-CDH1

Cat No
AAV-280631

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cdh1.

AAV-280631

AAV-m-CDH1

Ready-to-use AAV expressing Mouse Cdh1 (cadherin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AA960649; ARC-1; E-cad; Ecad; L-CAM; Um; UVO

Description (Vector)

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7|Function: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

Gene ID

12550

Gene Name (Vector)

cadherin 1

Gene Symbol

Cdh1

ORF Size (aa)

2655

ORF Size (bp)

2655 bp

RefSeq ID

NM_009864

RefSeq Synonyms

NM_009864, BC098501,

Species

mouse

UniGene ID

Mm.35605

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.