mouse BRSK2 Over-expression AAV

Name
AAV-m-BRSK2

Cat No
AAV-280326

Availability
4-5 weeks

This is an AAV expressing Mouse Brsk2.

AAV-280326

AAV-m-BRSK2

Ready-to-use AAV expressing Mouse Brsk2 (BR serine/threonine kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

4833424K13Rik; SAD-A; SADA

Description (Vector)

Serine/threonine-protein kinase that plays a key role in polarization of neurons. Phosphorylates MAPT/TAU and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-579'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons.

Gene ID

75770

Gene Name (Vector)

BR serine/threonine kinase 2

Gene Symbol

Brsk2

ORF Size (aa)

1962

ORF Size (bp)

1962 bp

RefSeq ID

NM_029426

RefSeq Synonyms

NM_029426, NM_001276763, NM_001009930, NM_001009929, BC166011,

Species

mouse

UniGene ID

Mm.274868

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.