mouse PIAS1 Over-expression AAV
This is an AAV expressing Mouse Pias1.
AAV-280068
AAV-m-PIAS1
Ready-to-use AAV expressing Mouse Pias1 (protein inhibitor of activated STAT 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2900068C24Rik; Ddxbp1; GBP
Description (Vector)
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Together with PRMT1, may repress STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling.
Gene ID
56469
Gene Name (Vector)
protein inhibitor of activated STAT 1
Gene Symbol
Pias1
ORF Size (aa)
1956
ORF Size (bp)
1956 bp
RefSeq ID
NM_019663
RefSeq Synonyms
NM_019663, BC051417,
Species
mouse
UniGene ID
Mm.478010
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.