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mouse ZFAND5 Over-expression AAV

Name 
AAV-m-ZFAND5
Cat No 
AAV-277866
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Zfand5.

AAV-277866
AAV-m-ZFAND5

Ready-to-use AAV expressing Mouse Zfand5 (zinc finger, AN1-type domain 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310057A04Rik; 5830475F03Rik; AA415485; Za20d2; Zfp216
Description (Vector)
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Gene ID
22682
Gene Name (Vector)
zinc finger, AN1-type domain 5
Gene Symbol
Zfand5
ORF Size (aa)
642
RefSeq ID
NM_009551
RefSeq Synonyms
NM_009551, BC119126, BC119124, BC107566,
Species
mouse
UniGene ID
Mm.292405

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.