mouse USP2 Over-expression AAV

Name 
AAV-m-USP2
Cat No 
AAV-275720
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Usp2.

AAV-275720
AAV-m-USP2

Ready-to-use AAV expressing Mouse Usp2 (ubiquitin specific peptidase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B930035K21Rik; Ubp41
Description (Vector)
Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells.
Gene ID
53376
Gene Name (Vector)
ubiquitin specific peptidase 2
Gene Symbol
Usp2
ORF Size (aa)
1860
ORF Size (bp)
1860 bp
RefSeq ID
NM_016808
RefSeq Synonyms
NM_198092, NM_198091, NM_016808, BC017517,
Species
mouse
UniGene ID
Mm.272770

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.