mouse TRPV6 Over-expression AAV

Name 
AAV-m-TRPV6
Cat No 
AAV-275112
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Trpv6.

AAV-275112
AAV-m-TRPV6

Ready-to-use AAV expressing Mouse Trpv6 (transient receptor potential cation channel, subfamily V, member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Cac; CAT; CaT1; Ecac2; Otrpc3
Description (Vector)
Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity).
Gene ID
64177
Gene Name (Vector)
transient receptor potential cation channel, subfamily V, member 6
Gene Symbol
Trpv6
ORF Size (aa)
2184
ORF Size (bp)
2184 bp
RefSeq ID
NM_022413
RefSeq Synonyms
NM_022413, BC016101,
Species
mouse
UniGene ID
Mm.296889

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.