mouse TRPV6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Trpv6.
shADV-275112
Ad-m-TRPV6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Trpv6 (transient receptor potential cation channel, subfamily V, member 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cac; CAT; CaT1; Ecac2; Otrpc3
Description (Vector)
Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity).
Gene ID
64177
Gene Name (Vector)
transient receptor potential cation channel, subfamily V, member 6
Gene Symbol
Trpv6
ORF Size (aa)
2184
ORF Size (bp)
2184 bp
RefSeq ID
NM_022413
RefSeq Synonyms
NM_022413, BC016101,
Species
mouse
UniGene ID
Mm.296889
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.